Published papers
LipoSEARCH has been accepted by prestigious scientific journals and is used by academic researchers in various fields such as metabolic endocrinology, pharmacology, physiology, neurochemistry, environmentology, and forensic medicine and by researchers in pharmaceutical industry and food industry.
<Published papers on the LipoSEARCH method>
Usui S, et al
A new on-line dual enzymatic method for simultaneous quantification of cholesterol and triglycerides in lipoproteins by HPLC.
J Lipid Res. 2002, 43(5), 805-814.
Okazaki M, et al
Identification of unique lipoprotein subclasses for visceral obesity by component analysis of cholesterol profile in HPLC.
Arterioscler Thromb Vasc Biol. 2005;25(3):578-584.
<Published papers that have used the LipoSEARCH method>
Miida T, et al
Probucol markedly reduces HDL phospholipids and elevated prebeta1-HDL without delayed conversion into alpha-migrating HDL: Putative role of angiopoietin-like protein 3 in probucol-induced HDL remodeling.
Atherosclerosis. 2008 Feb 13.
Nakata S, et al
Spontaneous myocardial infarction in mice lacking all nitric oxide synthase isoforms.
Circulation. 2008 Apr 29;117(17):2211-23. Epub 2008 Apr 14.Click here to read
Fujita H, et al
Low-density lipoprotein profile changes during the neonatal period.
Journal of Perinatology advance online publication 13 March 2008; doi: 10.1038/jp.2008.8
Fujita H, et al
Heterogeneity of high-density lipoprotein in cord blood and its postnatal change.
Clinica Chimica Acta Volume 389, Issues 1-2, March 2008, Pages 93-97.
W. Hu, et al
Biogenesis of HDL by SAA is dependent on ABCA1 in the liver in vivo.
J. Lipid Res., February 1, 2008; 49(2): 386 - 393.
Sasase T, et al
Increased fat absorption and impaired fat clearance cause postprandial hypertriglyceridemia in Spontaneously Diabetic Torii rat.
Diabetes Res Clin Pract. 2007 Oct;78(1):8-15.
Mastuzawa N, et al
Lipid-induced oxidative stress causes steatohepatitis in mice fed an atherogenic diet.
Hepatology. 2007 Nov;46(5):1392-403.
Saiki O, et al
Infliximab but not methotrexate induces extra-high levels of VLDL-triglyceride in patients with rheumatoid arthritis.
J Rheumatol. 2007 Oct;34(10):1997-2004
Oku H, et al
Adiponectin deficiency suppresses ABCA1 expression and ApoA-I synthesis in the liver.
FEBS Lett. 2007 Oct 30;581(26):5029-33.
Li J, et al
Hyperlipidemia and lipid peroxidation are dependent on the severity of chronic intermittent hypoxia.
J Appl Physiol. 2007 Feb;102(2):557-63
Sedova L, et al
Sucrose feeding during pregnancy and lactation elicits distinct metabolic response in offspring of an inbred genetic model of Metabolic Syndrome.
Am J Physiol Endocrinol Metab 2007 Jan 9 [Epub ahead of print]
Kobayashi M, et al
Prevention and treatment of obesity, insulin resistance, and diabetes by bile Acid-binding resin.
Diabetes 2007 Jan ;56(1):239-47
Gao J, et al
Involvement of apolipoprotein E in excess fat accumulation and insulin resistance.
Diabetes 2007 Jan ;56(1):24-33
Shimamura M, et al
Angiopoietin-Like Protein3 Regulates Plasma HDL Cholesterol through Suppression of Endothelial Lipase.
Arterioscler Thromb Vasc Biol. 2007 Feb;27(2):366-72. Epub 2006 Nov 16.
Okazaki M, et al
Component Analysis of HPLC Profiles of Unique Lipoprotein Subclass Cholesterols for Detection of Coronary Artery Disease.
Clin Chem , 2006; 52(11) 2049-2053.
Kawai T, et al
Hereditary Postprandial Hypertriglyceridemic Rabbit Exhibits Insulin Resistance and Central Obesity.
Arterioscler. Thromb. Vasc. Biol. 2006 Dec;26(12):2752-7
Gotsman I, et al
Impaired Regulatory T-cell response and enhanced atherosclerosis in the absence of inducible costimulatory molecule.
Circulation 2006 Nov 7;114(19):2047-55
Kohno M, et al
Decreases in Serum Triacylglycerol and Visceral Fat Mediated by Dietary Soybean β-conglycinin.
J Atheroscler Thromb 2006 ;13:247-255
Totani N, et al
Effects of Deteriorated Frying Oil in Wistar Rats.
Journal of Oleo Science Vol. 55 (2006) , No. 6 291-297
Totani N, et al
Effects of Deteriorated Frying Oil in SHR/NDmc-cp Rats.
Journal of Oleo Science Vol. 55 (2006) , No. 6 283-289
Abidi P, et al
The medicinal plant goldenseal is a natural LDL-lowering agent with multiple bioactive components and new action mechanisms.
J. Lipid Res. 2006 Oct;47(10):2134-47
Okazaki H, et al
Increased cholesterol biosynthesis and hypercholesterolemia in mice overexpressing squalene synthase in the liver.
J Lipid Res. 2006; 47(9):1950-8.
Seda O, et al
Novel double-congenic strain reveals effects of spontaneously hypertensive rat chromosome 2 on specific lipoprotein subfractions and adiposity.
Physiol. Genomics 2006 Oct 3;27(1):95-102
Abe-Dohmae.S, et al
Serum amyloid A generates high density lipoprotein with cellular lipid in an ABCA1- or ABCA7-dependent manner.
J. Lipid Res. 2006 Jul;47(7):1542-50
Yamamoto K, et al
Diacylglycerol ingestion in type 2-diabetic patients with hyperglyceridemia.
Nutrition, 2006;22(1):23-29
Mackness B, et al
Human Paraoxonase-1 Overexpression Inhibits Atherosclerosis in a Mouse Model of Metabolic Syndrome.
Arterioscler. Thromb. Vasc. Biol.2006 Jul;26(7):1545-50
Xuguo Sun, et al
Lipid droplets are present in amyloid deposits in familial amyloidotic polyneuropathy and dialysis related amyloidosis.
Amyloid. 2006 Mar;13(1):20-3
Y.M. Wang, et al
Short-term feeding of conjugated linoleic acid does not induce hepatic steatosis in C57BL/6J mice.
J. Nutr. Sci. Vitaminol.2005,51, 440-444
Hayashi.M, et al
Heterogeneity of high density lipoprotein generatede by ABCA1 and ABCA7.
J. Lipid Res. 2005 Aug;46(8):1703-11
Yamazaki T, et al
Increased Very Low Density Lipoprotein Secretion and Gonadal Fat Mass in Mice Overexpressing Liver DGAT1.
J. Biol. Chem.2005 Jun 3;280(22):21506-14
Isoda K, et al
Deficiency of interleukin-1 receptor antagonist deteriorates fatty liver and cholesterol metabolism in hypercholesterolemic mice.
J Biol Chem. 2005 Feb 25;280(8):7002-9
Niho N, et al
Concurrent suppression of hyperlipidemia and intestinal polyp formation by NO-1886, increasing lipoprotein lipase activity In Min mice.
Proc. Natl. Acad. Sci.2005 Feb 22;102(8):2970-4
Tsujita M, et al
On the hepatic mechanism of HDL assembly the ABCA1/apoA-1 pathway.
J. Lipid Res.2005 Jan;46(1):154-62
Harada-Shiba M, et al
Disruption of autosomal recessive hypercholesterolemia gene shows different phenotype in vitro and in vivo.
Circ Res. 2004 Oct 29;95(9):945-52
Niho N, et al
Dose-dependent suppression of hyperlipidemia and intestinal polyp formation in Min mice by pioglitazone,a PPARγligand.
Cancer Sci.2003 Nov;94(11):960-4
Magoori K, et al
Severe hypercholesterolemia, impaired fat tolerance, and advanced atherosclerosis in mice lacking both low density lipoprotein receptor-related protein 5 and apolipoprotein E.
J Biol Chem. 2003 Mar 28;278(13):11331-6
Wu CA, et al
Cholesteryl ester transfer protein expressed in lecithin cholesterol acyltransferase-deficient mice.
Arterioscler Thromb Vasc Biol. 2002 Aug 1;22(8):1347-53