Papers Using LipoSEARCH Profiles
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Published Papers Using LipoSEARCH Profiling Data
LipoSEARCH profiles have been accepted and used by academic researchers in broad range of fields such as metabolic endocrinology, pharmacology, physiology, neurochemistry, environmentology, and forensic medicine and by researchers in pharmaceutical industry and food industry
Published Papers on LipoSEARCH Methodology
| Mitsuyo Okazaki and Shizuya Yamashita Recent Advances in Analytical Methods on Lipoprotein Subclasses: Calculation of Particle Numbers from Lipid Levels by Gel Permeation HPLC Using “Spherical Particle Model” J.Oleo Sci. 65, (4) 265-282 (2016) |
| Toshima G, et al LipoSEARCH®; Analytical GP-HPLC method for lipoprotein profiling and its applications J.Biol.Macromol. 2013,13(2):21-32 |
| Usui S. et al A new on-line dual enzymatic method for simultaneous quantification of cholesterol and triglycerides in lipoproteins by HPLC. J Lipid Res. 2002, 43(5), 805-814. |
| Okazaki M. et al Identification of unique lipoprotein subclasses for visceral obesity by component analysis of cholesterol profile in HPLC. Arterioscler Thromb Vasc Biol. 2005;25(3):578-584. |
Published Papers Using LipoSEARCH Profile Data
| Kimura N, et al Species differences in lipoprotein lipase and hepatic lipase activities: comparative studies of animal models of lifestyle-related diseases. Exp Anim 2019 in press. |
| Yokote K, et al Long-Term Efficacy and Safety of Pemafibrate, a Novel Selective Peroxisome Proliferator-Activated Receptor-α Modulator (SPPARMα), in Dyslipidemic Patients with Renal Impairment. Int J Mol Sci 2019 in press. |
| Takanashi M, et al Critical Role of SREBP (Sterol Regulatory Element-Binding Protein)-1c Large-VLDL (Very Low-Density Lipoprotein) Pathway in Environment-Induced Hypertriglyceridemia of Apo AV Deficiency. Arterioscler Thromb Vasc Biol 2019 in press. |
| Takahashi Y, et al Tofu and fish oil independently modulate serum lipid profiles in rats: Analyses of 10 class lipoprotein profiles and the global hepatic transcriptome. PLos One 2019;14(1):e0210950 |
| Yokoji-Takeuchi M, et al Indirect regulation of PCSK9 gene in inflammatory response by Porphyromonas gingivalis infection. Heliyon 2019;5(1):e01111. |
| Shigetomi N, et al Determination of the Serum Unbound Fraction of Tadalafil in Children with Protein-Losing Enteropathy and Its Specific Binding to Human Serum Proteins in Vitro. Biol Pharm Bull 2019;42:110-115. |
| Singh AB, et al Identification of a novel function of hepatic long-chain acyl-CoA synthetase-1 (ACSL1) in bile acid synthesis and its regulation by bile acid-activated farnesoid X receptor. Biochim Biophys Acta 2018 in press |
| Nishitani S, et al Metabolomic Analysis of Diet-Induced Obese Mice Supplemented with Eicosapentaenoic Acid. Exp Clin Endocrinol Diabetes 2018 in press. |
| Seimiya A, et al Characterization of chylomicron in preterm infants. Pediatr Int 2018 in press. |
| Shibakami M, et al Creation of Straight-Chain Cationic Polysaccharide-Based Bile Salt Sequestrants Made from Euglenoid β-1,3-Glucan as Potential Antidiabetic Agents. Pharm Res 2019;36:23 |
| Mota R, et al 111In-DANBIRT In Vivo Molecular Imaging of Inflammatory Cells in Atherosclerosis. Contrast Media Mol Imaging 2018 in press. |
| Iizuka K, et al ChREBP Reciprocally Regulates Liver and Plasma Triacylglycerol Levels in Different Manners. Nutrients 2018;10(11):1699. |
| Igarashi M, et al NAPE-PLD controls OEA synthesis and fat absorption by regulating lipoprotein synthesis in an in vitro model of intestinal epithelial cells. FASEB J 2018 in press. |
| Masuyama A, et al Defective autophagy in vascular smooth muscle cells enhances atherosclerotic plaque instability. Biochem Biophys Res Commun 2018;505(4):1141-1147. |
| Nihei W, et al NPC1L1-dependent intestinal cholesterol absorption requires ganglioside GM3 in membrane microdomains. J Lipid Res 2018；59(11)：2182-2187. |
| Suganuma H, et al Influence of an intravenous lipid emulsion on lipoprotein subclasses in preterm infants. Pediatr Int 2018;60(9):839-843. |
| Tirronen A, et al Deletion of Lymphangiogenic and Angiogenic Growth Factor VEGF (Vascular Endothelial Growth Factor)-D Leads to Severe Hyperlipidemia and Delayed Clearance of CR (Chylomicron Remnants). Arterioscler Thromb Vasc Biol 2018;38(10):2327-2337. |
| Singh A, et al Farnesoid X Receptor Activation by Obeticholic Acid Elevates Liver Low-Density Lipoprotein Receptor Expression by mRNA Stabilization and Reduces Plasma Low-Density Lipoprotein Cholesterol in Mice. Arterioscler Thromb Vasc Biol 2018;38(10):2448-2459. |
| Nishino T, et al SREBF1/MicroRNA-33b Axis Exhibits Potent Effect on Unstable Atherosclerotic Plaque Formation In Vivo. Arterioscler Thromb Vasc Biol 2018;38(10):2460-2473. |
| Nozaki Y, et al Deficiency of eNOS exacerbates early-stage NAFLD pathogenesis by changing the fat distribution BMC Gastroenterol 2015;15:177 |
| Izumi R, et al CRISPR/Cas9-mediated Angptl8 knockout suppresses plasma triglyceride concentrations and adiposity in rats. J Lipid Res 2018;59(9):1575-1585. |
| Yamashita S, et al Effects of pemafibrate (K-877) on cholesterol efflux capacity and postprandial hyperlipidemia in patients with atherogenic dyslipidemia. J Clin Lipidol 2018;12(5):1267-1279. |
| Watanabe T, et al Lp8 is potentially associated with partial lecithin: cholesterol acyltransferase deficiency in a patient with primary biliary cirrhosis. J Clin Lipidol 2018;12(5):1157-1163. |
| Komatus M, et al NNMT activation can contribute to the development of fatty liver disease by modulating the NAD+ metabolism. Sci Rep 2018;8(1):8637. |
| Yamashita Y, et al Perlecan, a heparan sulfate proteoglycan, regulates systemic metabolism with dynamic changes in adipose tissue and skeletal muscle. Sci Rep. 2018;8(1):7766. |
| Yang M, et al Apolipoprotein A-II induces acute-phase response associated AA amyloidosis in mice through conformational changes of plasma lipoprotein structure. Sci Rep 2018;8(1):5620. |
| Niwa H, et al ChREBP Rather Than SHP Regulates Hepatic VLDL Secretion. Nutrients 2018;10(3):321. |
| Sato Y, et al Clinofibrate improved canine lipid metabolism in some but not all breeds. J Vet Med Sci 2018; 80(6): 1034-1040 |
| Hara T, et al Progression of calcific aortic valve sclerosis in WHHLMI rabbits. Atherosclerosis 2018;273:8-14. |
| Papazyan R, et al FXR activation by obeticholic acid or non-steroidal agonists induces a human-like lipoprotein cholesterol change in mice with humanized chimeric liver. J Lipid Res 2018;59(6):982-993. |
| Shinozawa E, et al Antidyslipidemic potential of a novel farnesoid X receptor antagonist in a hamster model of dyslipidemia: Comparative studies of other nonstatin agents. Pharmacol Res Perspect 2018;6(2):e00390. |
| Ide K, et al N-3 polyunsaturated fatty acids improve lipoprotein particle size and concentration in Japanese patients with type 2 diabetes and hypertriglyceridemia: a pilot study. Lipids Health Dis 2018;17(1):51 |
| Kawakami R, et al Development of vaccine for dyslipidemia targeted to a proprotein convertase subtilisin/kexin type 9 (PCSK9) epitope in mice. PLoS One. 2018;13(2):e0191895 |
| Konishi T and Takahashi Y Lipoproteins comprise at least 10 different classes in rats, each of which contains a unique set of proteins as the primary component. PLoS One. 2018,13(2):e0192955. |
| Hayashi Y, et al FADS2 inhibition in essential fatty acid deficiency induces hepatic lipid accumulation via impairment of very low-density lipoprotein (VLDL) secretion. Biochem Biophys Res Commun 2018;496(2):549-555. |
| Kvalheim OM, et al Determination of optimum number of components in partial least squares regression from distributions of the root‐mean‐squared error obtained by Monte Carlo resampling. J Chemometr 2018:e2993 |
| Jacobs DM, et al Effect of Theobromine Consumption on Serum Lipoprotein Profiles in Apparently Healthy Humans with Low HDL-Cholesterol Concentrations. Front Mol Biosci 2017;4:59. |
| Seda O, et al Connexin 50 mutation lowers blood pressure in spontaneously hypertensive rat. Physiol Res. 2017;66(1):15-28. |
| Araki R, et al Effect of partially-abraded brown rice consumption on body weight and the indicators of glucose and lipid metabolism in pre-diabetic adults: A randomized controlled trial. Clinical Nutrition ESPEN,2017; 19: 9-15. |
| Komiya M, et al Suppressive effects of the NADPH oxidase inhibitor apocynin on intestinal tumorigenesis in obese KK-Ay and Apc mutant Min mice. Cancer Sci 2015;106:1499-1505. |
| Ishiguro K, et al Effects of a sweetpotato protein digest on lipid metabolism in mice administered a high-fat diet. Heliyon.2016 ;2(12):e00201. |
| Ozawa, et al. Influence of δ-Amino levulinic acid on body fat, body weight, and blood property in diet induced obese dogs. Journal of Pet Animal Nutrition 2015;18(1):18-24. |
| Okada T,et al Particle number analysis of lipoprotein subclasses by gel permeation HPLC in patients with cholesteryl ester transfer protein deficiency. PLos One 2018;13(1):e0190875 |
| Akita K, et al An interleukin-6 receptor antibody suppresses atherosclerosis in atherogenic mice. Front Cardiovasc Med 2017;4:84 |
| Silbernagel G, et al High-density lipoprotein subclasses, coronary artery disease, and cardiovascular mortality. Clin Chem 2017;63(12):1886-1896. |
| Kikai M, et al Transplantation of brown adipose tissue inhibits atherosclerosis in apoE-/- mice: contribution of the activated FGF-21-adiponectin axis. Cardiovasc Res 2018;114(6):i1-i13. |
| Sairyo M, et al A Novel Selective PPARα Modulator (SPPARMα), K-877 (Pemafibrate), Attenuates Postprandial Hypertriglyceridemia in Mice. J Atheroscler Thromb 2018;25(2):142-152. |
| Hirano Y, et al Surfactant Protein D Deficiency Suppresses Systemic Inflammation and Reduces Atherosclerosis in ApoE Knockout Mice. Cardiovasc Res 2017;113(10):1208-1218. |
| Wang Z, et al Comparative studies of three cholesteryl ester transfer proteins and their interactions with known inhibitors. PLoS One 2017;12(8):e0180772. |
| Takashima A, et al In vitro and in vivo antidiabetic effects of the ethanol extract from Lentinula edodes (Shiitake) Nutrafoods 2016;15:279-284 |
| Suto A, et al LC-MS/MS analysis of canine lipoproteins fractionated using the ultracentrifugation-precipitation method. J Vet Med Sci. 2013 ;75(11):1471-1477. |
| Morino S, et al Mild electrical stimulation with heat shock ameliorates insulin resistance via enhanced insulin signaling. PloS one 3.12 2008 3;12:e4068 |
| Akahoshi N, et al Genetic background conversion ameliorates semi-lethality and permits behavioral analyses in cystathionine β-synthase-deficient mice, an animal model for hyperhomocysteinemia. Hum Mol Genet 2008 17;13:1994-2005 |
| Sumiyoshi K, et al Deletion of the Fc receptors γ chain preserves endothelial function affected by hypercholesterolaemia in mice fed on a high-fat diet Cardiovasc Res 2008 80;3:463-470 |
| Hyohun Park, et al Efficacy of long-term ezetimibe therapy in patients with nonalcoholic fatty liver disease J Gastroenterol 2011 46;1:101-107. |
| Sasaki A, et al. Lipoprotein profiles of hepatic cell lines at various stages of differentiation. In Vitro Cellular ＆ Developmental Biology-Animal, 2017;53(2):93-95. |
| Takahashi T, et al. Analysis of cholesterol lipoprotein separations in Holstein dairy cattle by anion-exchange high-performance liquid chromatography. J Pet Anim Nutr 2017;20(1):30-38. |
| Hirata H, et al Xanthohumol, a Hop-derived Prenylated Flavonoid, Promotes Macrophage Reverse Cholesterol Transport J Nutr Biochem 2017;47:29-34. |
| Shinnakasu A, et al The Combination Therapy of Fenofibrate and Ezetimibe Improved Lipid Profile and Vascular Function Compared with Statins in Patients with Type 2 Diabetes J Atheroscler Thromb 2017;24(7)：735-748. |
| Geir Kåre Resaland, et al Strong association between cardiorespiratory fitness and serum lipoprotein subclass pattern in prepubertal healthy children Scand J Med Sci Sports 2017;28(1):220-227. |
| Oue K, et al Phospholipase C-related catalytically inactive protein-knockout mice exhibit uncoupling protein 1 upregulation in adipose tissues following chronic cold exposure. J Oral Biosci 2017;59:108-112. 2017 |
| Oda H, et al Cholesterol concentrations in lipoprotein fractions separated by anion-exchange–high-performance liquid chromatography in healthy dogs and dogs with hypercholesterolemia Res Vet Sci 2017;114:163-169. |
| Watanabe S, et al Daily Coffee Intake Inhibits Pancreatic Beta Cell Damage and Nonalcoholic Steatohepatitis in a Mouse Model of Spontaneous Metabolic Syndrome,Tsumura-Suzuki Obese Diabetic Mice Metab Syndr Relat Disord 2017;15(4):170-177. |
| Kina-Tanada M, et al Long-term dietary nitrite and nitrate deficiency causes the metabolic syndrome, endothelial dysfunction and cardiovascular death in mice Diabetologia 2017:60(6):1138-1151. |
| Amano A, et al Abnormal lipid/lipoprotein metabolism and high plasma testosterone levels in male but not female aromatase-knockout mice Arch Biochem Biophys 2017;622:47-58. |
| Kim N, et al Effect of lipid metabolism on male fertility Biochem Biophys Res Commun. 2017 Apr 8;485(3):686-692. |
| Monguchi T, et al Excessive intake of trans fatty acid accelerates atherosclerosis through promoting inflammation and oxidative stress in a mouse model of hyperlipidemia J Cardiol. 2017;70(2):121-127. |
| Ito F, et al The Application of a Modified d-ROMs Test for Measurement of Oxidative Stress and Oxidized High-Density Lipoprotein Int J Mol Sci. 2017 Feb 21;18(2) |
| Satou T, et al The Effect of Camellia Seed Oil Intake on Lipid Metabolism in Mice. Nat Prod Commun. 2016 Apr;11(4):511-3. |
| Li Y, et al Development of Human‐Like Advanced Coronary Plaques in Low‐Density Lipoprotein Receptor Knockout Pigs and Justification for Statin Treatment Before Formation of Atherosclerotic Plaques J Am Heart Assoc. 2016 Apr 18;5(4):e002779. |
| Kamada Y, et al Hepatic aberrant glycosylation by N-acetylglucosaminyltransferase V accelerates HDL assembly Am J Physiol Gastrointest Liver Physiol. 2016 Nov 1;311(5):G859-G868. |
| Seda O, et al Heterozygous connexin 50 mutation affects metabolic syndrome attributes in spontaneously hypertensive rat Lipids Health Dis. 2016 Nov 21;15(1):199. |
| Deushi M, et al Ezetimibe reduced hepatic steatosis induced by dietary oxysterols in nonhuman primates FEBS Open Bio. 2016 Sep 20;6(10):1008-1015. |
| Yondeda T, et al Preventive Effects of Drinking Hydrogen-Rich Water on Gingival Oxidative Stress and Alveolar Bone Resorption in Rats Fed a High-Fat Diet. Nutrients. 2017 Jan 13;9(1),64 |
| Kasahara K, et al Commensal Bacteria at the Crossroad between Cholesterol Homeostasis and Chronic Inflammation in Atherosclerosis J Lipid Res. 2017,58(3):519-528. |
| Ishikawa A Identification of a Putative Quantitative Trait Gene for Resistance to Obesity in Mice Using Transcriptome Analysis and Causal Inference Tests. PLoS One. 2017 Jan 23;12(1):e0170652. |
| Honda T, et al Branched-chain amino acids alleviate hepatic steatosis and liver injury in choline-deficient high-fat diet induced NASH mice Metabolism 2017,69:177-187. |
| Oikawa S, et al Efficacy and Safety of Long-term Coadministration of Fenofibrate and Ezetimibe in Patients with Combined Hyperlipidemia: Results of the EFECTL Study. J Atheroscler Thromb. 2017 Jan 1;24(1):77-94. |
| Ikeda T, et al A rapid and precise method for measuring plasma apoE-rich HDL using polyethylene glycol and cation-exchange chromatography: a pilot study on the clinical significance of apoE-rich HDL measurements. Clin Chim Acta. 2016 Dec 18;465:112-118. |
| Al Mamun A, et al Effect of dietary n-3 fatty acids supplementation on fatty acid metabolism in atorvastatin-administered SHR.Cg-Leprcp/NDmcr rats, a metabolic syndrome model. Biomed Pharmacother. 2017 Jan;85:372-379. |
| Singh AB and Liu J Identification of Hepatic Lysophosphatidylcholine Acyltransferase 3 as a Novel Target Gene Regulated by Peroxisome Proliferator-activated Receptor δ. J Biol Chem. 2017 Jan 20;292(3):884-897. |
| Dong B, et al Regulation of lipid metabolism by obeticholic acid in hyperlipidemic hamsters. J Lipid Res. 2017,58(2):350-363. |
| Dong B, et al CETP inhibitors downregulate hepatic LDL receptor and PCSK9 expression in vitro and in vivo through a SREBP2 dependent mechanism. Atherosclerosis. 2014 Aug;235(2):449-62. |
| O’Donnell PE, et al Lipodystrophy, Diabetes and Normal Serum Insulin in PPARγ-Deficient Neonatal Mice. PLoS One. 2016 Aug 9;11(8):e0160636. |
| Miyazaki T, et al Calpain-6 confers atherogenicity to macrophages by dysregulating pre-mRNA splicing. J Clin Invest. 2016 Sep 1;126(9):3417-32. |
| Fernandes P, et al Solithromycin Diminishes Steatohepatitis by Modulating Gluconeogenesis and Inhibits Tumor Growth in a Diabetic Mouse Model of Non-Alcoholic Steatohepatitis J Immunol Infect Inflam Dis. 2016 (1) 1,004 |
| Alberts-Grill N, et al Dendritic Cell KLF2 Expression Regulates T Cell Activation and Proatherogenic Immune Responses. J Immunol. 2016 Dec 15;197(12):4651-4662. |
| Kanda E, et al Association of High-Density Lipoprotein Subclasses with Chronic Kidney Disease Progression, Atherosclerosis, and Klotho. PLoS One. 2016 Nov 18;11(11):e0166459. |
| Kinoshita C, et al Hepatitis C virus G1b infection decreases the number of small low-density lipoprotein particles. World J Gastroenterol. 2016 Aug 7;22(29):6716-25. |
| Yamada S, et al Novel function of histamine signaling via histamine receptors in cholesterol and bile acid metabolism: Histamine H2 receptor protects against nonalcoholic fatty liver disease. Pathol Int. 2016 Jul;66(7):376-85. |
| Nakagawa Y, et al Hyperlipidemia and hepatitis in liver-specific CREB3L3 knockout mice generated using a one-step CRISPR/Cas9 system. Sci Rep. 2016 Jun 13;6:27857. |
| Mizutani H, et al Analysis of lipoprotein profiles of healthy cats by gel-permeation high-performance liquid chromatography. J Vet Med Sci. 2016 Sep 1;78(8):1277-81. |
| Li Y, et al Development of Human-Like Advanced Coronary Plaques in Low-Density Lipoprotein Receptor Knockout Pigs and Justification for Statin Treatment Before Formation of Atherosclerotic Plaques. J Am Heart Assoc. 2016 Apr 18;5(4):e002779. |
| Sato R, et al Fetal Environment and Glycosylation Status in Neonatal Cord Blood: A Comprehensive Mass Spectrometry-based Glycosylation Analysis. Medicine (Baltimore). 2016 Apr;95(14):e3219. |
| Nawata A, et al Overexpression of Peroxiredoxin 4 Affects Intestinal Function in a Dietary Mouse Model of Nonalcoholic Fatty Liver Disease. PLoS One. 2016 Apr 1;11(4):e0152549. |
| Hirano T, et al Anagliptin, a dipeptidyl peptidase-4 inhibitor, decreases macrophage infiltration and suppresses atherosclerosis in aortic and coronary arteries in cholesterol-fed rabbits. Metabolism. 2016 Jun;65(6):893-903. |
| Abe Y, et al Abdominal Obesity, Insulin Resistance, and Very Low-Density Lipoprotein Subclass Profile in Japanese School Children J Child Obese. 2016(1)1-3 |
| Rajalahti T, et al Serum fatty acid and lipoprotein subclass concentrations and their associations in prepubertal healthy Norwegian children Metabolomics. 2016; 12: 81. |
| Ishibashi S, et al Effects of K-877, a novel selective PPARα modulator (SPPARMα), in dyslipidaemic patients: A randomized, double blind, active- and placebo-controlled, phase 2 trial Atherosclerosis. 2016 Jun;249:36-43. |
| Satoh K, et al High level of serum cholesteryl ester transfer protein in active hepatitis C virus infection World J Hepatol. 2016 Feb 18; 8(5): 291–300. |
| Deng X, et al iPLA2β deficiency attenuates obesity and hepatic steatosis in ob/ob mice through hepatic fatty-acyl phospholipid remodeling. Biochim Biophys Acta. 2016:1861(5):449-461. |
| Rajalahti T, et al Changes in serum fatty acid and lipoprotein subclass concentrations from prepuberty to adulthood and during aging. Metabolomics. 2016; 12:51 |
| Lin C, et al Predictive associations between serum fatty acids and lipoproteins in healthy non-obese Norwegians: implications for cardiovascular health. Metabolomics. 2016;12(1):6 |
| Niimi M, et al ApoE knockout rabbits: A novel model for the study of human hyperlipidemia. Atherosclerosis. 2016 ;245:187-93. |
| Murano T, et al Subfraction analysis of circulating lipoproteins in a patient with Tangier due to a novel ABCA1 mutation. Clin Chim Acta. 2016 ;452:167-72. |
| Kuba M, et al Absence of Elovl6 attenuates steatohepatitis but promotes gallstone formation in a lithogenic diet-fed Ldlr(-/-) mouse model. Sci Rep. 2015 ;5:17604. |
| Muramatsu-Kato K, et al Undernourishment in utero Primes Hepatic Steatosis in Adult Mice Offspring on an Obesogenic Diet; Involvement of Endoplasmic Reticulum Stress. Sci Rep. 2015 ;5:16867. |
| Kobayashi K, et al Hepatocyte β-Klotho regulates lipid homeostasis but not body weight in mice. FASEB J. 2016 ;30(2):849-62. |
| Velsko IM, et al Periodontal pathogens invade gingiva and aortic adventitia and elicit inflammasome activation in αvβ6 integrin-deficient mice Infect Immun. 2015 ;83(12):4582-93. |
| Nagano T, et al Impact of Chronic Hepatitis C Virus Genotype 1b Infection on Triglyceride Concentration in Serum Lipoprotein Fractions. Int J Mol Sci. 2015 ;16(9):20576-94. |
| Kato R, et al Cardiovascular protection by ezetimibe and influence on oxidative stress in mice exposed to intermittent hypoxia. Eur J Pharmacol. 2015 ;765:7-14. |
| Li J, et al Identification of the Flavonoid Luteolin as a Repressor of the Transcription Factor Hepatocyte Nuclear Factor 4α. J Biol Chem. 2015 ;290(39):24021-35. |
| Uno K, et al A hepatic amino acid/mTOR/S6K-dependent signalling pathway modulates systemic lipid metabolism via neuronal signals Nat Commun. 2015 ;6:7940. |
| Nishina K, et al DNA/RNA heteroduplex oligonucleotide for highly efficient gene silencing. Nat Commun. 2015 ;6:7969. |
| Azuma K, et al Effects of Surface-Deacetylated Chitin Nanofibers in an Experimental Model of Hypercholesterolemia. Int J Mol Sci. 2015 ;16(8):17445-55. |
| Miyata S, et al Xanthohumol improves diet-induced obesity and fatty liver by suppressing sterol regulatory element-binding protein (SREBP) activation. J Biol Chem. 2015 ;290(33):20565-79. |
| Kayama K, et al Apolipoprotein A-V concentration in preterm infants. J Clin Lipidol. 2015 ;9(5):647-51. |
| Yoshihara T, et al Omega 3 Polyunsaturated Fatty Acids Suppress the Development of Aortic Aneurysms Through the Inhibition of Macrophage-Mediated Inflammation. Circ J. 2015;79(7):1470-8. |
| Usui S, et al Lipoprotein cholesterol and triglyceride concentrations associated with dog body condition score; effect of recommended fasting duration on sample concentrations in Japanese private clinics J Vet Med Sci. 2015 ;77(9):1063-9. |
| Fukuda K, et al Statins meditate anti-atherosclerotic action in smooth muscle cells by peroxisome proliferator-activated receptor-γ activation. Biochem Biophys Res Commun. 2015 ;457(1):23-30. |
| Yamada S, et al Novel function of histamine signaling in hyperlipidemia-induced atherosclerosis: Histamine H1 receptors protect and H2 receptors accelerate atherosclerosis. Pathol Int. 2015 ;65(2):67-80. |
| Shimizu T, et al Newly developed apolipoprotein A-I mimetic peptide promotes macrophage reverse cholesterol transport in vivo. Int J Cardiol. 2015 ;192:82-8. |
| Akita K, et al Dipeptidyl-peptidase-4 inhibitor, alogliptin, attenuates arterial inflammation and neointimal formation after injury in low-density lipoprotein (LDL) receptor-deficient mice. J Am Heart Assoc. 2015 ;4(3):e001469. |
| Hashidate-Yoshida T, et al Fatty acid remodeling by LPCAT3 enriches arachidonate in phospholipid membranes and regulates triglyceride transport. Elife. 2015 ;4. |
| Velsko IM, et al Fusobacterium nucleatum Alters Atherosclerosis Risk Factors and Enhances Inflammatory Markers with an Atheroprotective Immune Response in ApoEnull Mice. PLoS One. 2015 ;10(6):e0129795. |
| Kouda K, et al HDL subclasses are heterogeneous in their associations with body fat, as measured by dual-energy X-ray absorptiometry: The Kitakata Kids Health Study. Clin Chim Acta. 2015 ;444:101-5. |
| Makishima S, et al Sin3A-associated protein, 18 kDa, a novel binding partner of TRIB1, regulates MTTP expression. J Lipid Res. 2015 ;56(6):1145-52. |
| Imai N, et al Hepatocyte-Specific Depletion of UBXD8 Induces Periportal Steatosis in Mice Fed a High-Fat Diet. PLoS One. 2015 ;10(5):e0127114. |
| Nozaki Y, et al Deficiency of iNOS-derived NO accelerates lipid accumulation-independent liver fibrosis in non-alcoholic steatohepatitis mouse model. BMC Gastroenterol. 2015 ;15:42. |
| Noda K, et al Opposing roles of nitric oxide and rho-kinase in lipid metabolism in mice. Tohoku J Exp Med. 2015;235(3):171-83. |
| Yoshinaga K, et al Differential effects of triacylglycerol positional isomers containing n-3 series highly unsaturated fatty acids on lipid metabolism in C57BL/6J mice. J Nutr Biochem. 2015 ;26(1):57-63. |
| Kohjima M, et al Pathophysiological analysis of primary biliary cirrhosis focusing on choline/phospholipid metabolism. Liver Int. 2015 ;35(3):1095-102. |
| Okumura K, et al High HDL cholesterol level after treatment with pitavastatin is an important factor for regression in carotid intima–media thickness. Heart Vessels. 2015 ;30(2):154-61. |
| Hodulova M, et al Genomic determinants of triglyceride and cholesterol distribution into lipoprotein fractions in the rat. PLoS One. 2014 ;9(10):e109983. |
| Handa K, et al Long-term low carbohydrate diet leads to deleterious metabolic manifestations in diabetic mice. PLoS One. 2014 ;9(8):e104948. |
| Krupkova M, et al Pharmacogenomic analysis of retinoic-acid induced dyslipidemia in congenic rat model. Lipids Health Dis. 2014 ;13:172. |
| Miyoshi T, et al Omega-3 fatty acids improve postprandial lipemia and associated endothelial dysfunction in healthy individuals - a randomized cross-over trial. Biomed Pharmacother. 2014;68(8):1071-7. |
| Ekuni D, et al Occlusal disharmony accelerates the initiation of atherosclerosis in apoE knockout rats. Lipids Health Dis. 2014 ;13:144. |
| Yamakawa T, et al Colestimide improves glycemic control via hepatic glucose production in db/db mice. Endocr J. 2014;61(5):425-36. |
| Miyazaki T, et al The high molecular weight adiponectin level is associated with the atherogenic lipoprotein profiles in healthy Japanese males. J Atheroscler Thromb. 2014;21(7):672-9. |
| van Schalkwijk DB, et al Dietary Medium Chain Fatty Acid Supplementation Leads to Reduced VLDL Lipolysis and Uptake Rates in Comparison to Linoleic Acid Supplementation. PLoS One. 2014 ;9(7):e100376. |
| Yoshino S, et al Protection against High-fat Diet-induced Obesity in Helz2-deficient Male Mice due to Enhanced Expression of Hepatic Leptin Receptor. Endocrinology. 2014 ;155(9):3459-72. |
| Tanaka T, et al PPAR beta/delta activation of CD300a controls intestinal immunity. Sci Rep. 2014 ;4:5412. |
| Horie T, et al MicroRNA-33b knock-in mice for an intron of sterol regulatory element-binding factor 1 (Srebf1) exhibit reduced HDL-C in vivo. Sci Rep. 2014; 4: 5312. |
| Hirano K, et al Disease-associated marked hyperalphalipoproteinemia. Molecular Genetics and Metabolism Reports 12/2014; 1(1):264–268. |
| Kuroda M, et al Lipoprotein Subfractions Highly Associated With Renal Damage in Familial Lecithin:Cholesterol Acyltransferase Deficiency. Arterioscler Thromb Vasc Biol. 2014; 34(8): 1756-62. |
| Sato H, et al The Adipocyte-Inducible Secreted Phospholipases PLA2G5 and PLA2G2E Play Distinct Roles in Obesity. Cell Metab. 2014; 20(1): 119-32. |
| Mattijssen F, et al Hypoxia inducible lipid droplet associated (HILPDA) is a novel peroxisome proliferator-activated receptor (PPAR) target involved in hepatic triglyceride secretion. J Biol Chem. 2014; 289(28): 19279-93. |
| Yu Q, et al Effects of Antisense Oligonucleotides against C-Reactive Protein on the Development of Atherosclerosis in WHHL Rabbits Mediators Inflamm. 2014; 2014: 979132. |
| Velsko IM, et al Active Invasion of Oral and Aortic Tissues by Porphyromonas gingivalis in Mice Causally Links Periodontitis and Atherosclerosis. PLoS One. 2014; 9(5): e97811. |
| Yasunari E, et al Repetitive hypoglycemia increases circulating adrenaline level with resultant worsening of intimal thickening after vascular injury in male Goto-Kakizaki rat carotid artery. Endocrinology. 2014; 155(6): 2244-53. |
| Hamada M, et al MafB promotes atherosclerosis by inhibiting foam-cell apoptosis. Nat Commun. 2014;5:3147. |
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