Lipoprotein Profile Based on Particle Size

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Lipoprotein Profiles with More Meaningful Analysis Data

To provide scientists, researchers and clinicians with more meaningful analysis data, LipoSEARCH employs two unique technologies; gel-filtration HPLC (High Performance Liquid Chromatography) and its proprietary data processing algorithm.

Lipoprotein profiling is performed in the following three steps.

1. The sample is loaded into a gel permeation column specifically designed for separating lipoprotein components. Then, lipoprotein is eluted from the column in order of larger particles to smaller ones.
2. Lipoprotein fractionated by particle size is fed into reaction coils, and the degraded products after reacting with reagents are sent to detectors. The levels of cholesterol and triglyceride are output in the form of chromatogram.
3. The data obtained is processed with our patented analyzing program. The final output is a composite chromatogram and numeric data on 4 major classes (CM, VLDL, LDL and HDL) and 20 subclasses.
LipoSEARCH Chromatogram Analyzing Algorithm
Numeric data of 20 subclasses of lipoprotein is led by Gaussian approximation of raw chromatogram data measured with our gel-filtration HPLC.
The analyzing algorithm is patented in US and Japan and pending in EU and other countries.

LipoSEARCH Workflow

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