Complete and Accurate Lipoprotein Profile

About LipoSEARCH

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LipoSEARCH Advantages over Conventional Testing Methods

With proprietary gel-filtration HPLC (High Performance Liquid chromatography) and patented analyzing algorithm, LipoSEARCH offers remarkable advantages over conventional testing methods. The benefits brought on by LipoSEARCH are:

Complete and accurate data of cholesterol and TG (triglyceride) levels on 4 major classes (CM, VLDL, LDL and HDL) and 20 subclasses,

Size-based separation allows more accurate measurement of lipoprotein particle size,

Small sample requirement enables time-course studies while keeping valuable test animals alive,

Broad coverage of sample types; serum, plasma, culture supernatant and cerebrospinal fluid from human to small animals,

Test data is readily validated by high reproducibility, and

Quick turnaround – 5 working days.

Compare LipoSEARCH vs. Other Analytical Methods

Method LipoSEARCH
(HPLC)
Ultracentrifugation 1D Electrophoreisis
(GGE)
Direct Method NMR
Separation Mode Particle Size Specific Gravity Electric Charge Enzymic Reaction Magnetic Resonance
Sample 0.01ml 0.7ml 0.05ml 1ml 0.6ml
Testing Time 25 min. Over 270 min. 30 min. 10 min. 1min.
Major Classes
CM
VLDL
LDL
HDL
Subclasses
VLDL subclass
LDL subclass
HDL subclass
Particle Size
Particle Count
Fractionation
Reproducibility
Quantitativeness
Cost
Advantages ・Less sample requirement
・Size-based separation
・Complete data including 20subclasses
Gold standard of Lipid Profile Advantages in qualitative assay of major classes Simple and low cost Subclass analysis and Particle count available
Drawbacks Throughput in multiple samples testing Labor intensive ・Not good for quantitative analysis
・Error between gel lots
・Errors between reagents (LDL)
・Not good for sunbclass analysis
・Complicated computation process based on assumptions
・Expensive instrument

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