LipoSEARCH provides more comprehensive and clearer analyses of lipoprotein profiling, including the measurement of lipoprotein particle size.
Measurements of HDL cholesterol, LDL cholesterol, and TG are insufficient for the prevention and treatment of cardiovascular diseases. The importance of measuring lipoprotein particle sizes has been pointed out by academicians, with a focus on LDLs with small particle sizes, the so-called small dense LDLs that are believed to contribute to the development of atherosclerosis.
LipoSEARCH provides chromatograms with which it is possible to visually understand whether samples are normal or not. Further, data on cholesterol and TG levels of each fraction and on lipoprotein particle sizes are provided.
Diabetic patient
Pattern No. 36 from SLB library
VLDL peak of TG is characteristic of diabetic patients.
VLDL, which is rich in TG, increases as TG metabolism decreases due to lower LPL activity.
Healthy human(adult male)
Pattern No. 50 from SLB library
Patient with a low HDL level
Pattern No. 38 from SLB library
No HDL peak is observed.
Patient with hyperlipidemia
Pattern No. 60 from SLB library
VLDL and LDL cholesterol increased.
>> Examples of analysis for small animal sample